Why Consider Taking L-arginine and L-citrulline Together?
Why Consider Taking L-arginine and L-citrulline Together?

Why Consider Taking L-arginine and L-citrulline Together?

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Are you looking for an efficient way to improve your cardiovascular health, enhance athletic performance, or manage erectile dysfunction? L-arginine and L-citrulline are two amino acids that can help you achieve your health goals. But did you know that taking them together may offer even more benefits than taking them separately?

In this blog, we will dive deeper into what L-arginine and L-citrulline are, how they work together to boost nitric oxide production, the benefits of taking them in combination, and how to incorporate them into your daily routine for optimal results. Read on to discover the potential of this powerful duo.

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What are L-arginine and L-citrulline?

L-arginine and L-citrulline are two amino acids that play vital roles in the body. L-Arginine helps to produce nitric oxide in the body, which has several health benefits such as improved circulation, muscle growth, and exercise performance, to name a few. In contrast, L-Citrulline is naturally found in food and can be converted to L-Arginine in the body.

Taking L-arginine and L-citrulline supplements together can boost nitric oxide levels significantly more than taking each supplement alone. A combination of L-Arginine and L-Citrulline supplements provides the body with an immediate supply of L-Arginine and a precursor for sustained benefits. This combination can lead to superior health benefits, such as improved cardiovascular health, enhanced athletic performance, and better overall health.

How are L-arginine and L-citrulline Connected?

L-arginine and L-citrulline are both amino acids that are involved in the production of nitric oxide (NO) in the body. Nitric oxide is a gas that is involved in many physiological processes, including the regulation of blood flow, immune response, and neural signaling.

L-arginine is a precursor to nitric oxide synthesis in the body. When L-arginine is converted to nitric oxide, it causes the smooth muscle cells in blood vessels to relax, which in turn increases blood flow to various organs and tissues in the body. However, the conversion of L-arginine to nitric oxide requires the activity of an enzyme called nitric oxide synthase (NOS).

L-citrulline is another amino acid that is involved in the production of nitric oxide in the body. Unlike L-arginine, L-citrulline is not directly converted into nitric oxide. Instead, L-citrulline is converted into L-arginine in the kidneys and other tissues, which can then be used for nitric oxide synthesis. This conversion process is mediated by an enzyme called argininosuccinate synthase (ASS), which combines L-citrulline with another amino acid called aspartate to produce L-arginine.

So overall, L-arginine and L-citrulline are connected in the production of nitric oxide in the body. L-arginine is a direct precursor to nitric oxide synthesis, while L-citrulline is converted into L-arginine through a series of enzymatic reactions. Together, these two amino acids play an important role in regulating blood flow, immune response, and neural signaling in the body.

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Benefits of Taking L-Arginine and L-Citrulline Together

L-arginine and L-citrulline are two amino acids that have been studied for their potential health benefits. When taken together, they may offer several benefits due to their complementary effects on the body's production of nitric oxide.

Here are some potential benefits of taking L-arginine and L-citrulline together:

Nitric Oxide

Nitric oxide is a molecule that helps to dilate blood vessels, allowing for improved blood flow to various parts of the body. Both L-arginine and L-citrulline are involved in the production of nitric oxide, with L-arginine being a precursor to nitric oxide and L-citrulline being converted to L-arginine in the body.

Improved blood flow

As mentioned, both amino acids play a role in the production of nitric oxide, which can help to improve blood flow. This may be beneficial for athletes looking to improve their performance, as well as for people with conditions that affect blood flow, such as erectile dysfunction or peripheral artery disease.

Lowered blood pressure

The improved blood flow that results from increased nitric oxide production can also help to lower blood pressure. Studies have shown that supplementation with L-arginine and L-citrulline can lead to modest reductions in blood pressure in people with hypertension.

Enhanced exercise performance: Nitric oxide has been shown to improve exercise performance by increasing blood flow and oxygen delivery to muscles. Some studies have suggested that supplementation with L-arginine and L-citrulline can lead to improvements in endurance and power output during exercise.

Improved immune function

L-arginine and L-citrulline have been shown to have immunomodulatory effects, meaning they can help to regulate the immune system. This may be beneficial for people with autoimmune diseases or those who are looking to support their immune function.

If you're looking to boost your cardiovascular health or improve your athletic performance, you may want to consider taking L-arginine and L-citrulline together. L-citrulline converts into L-arginine in the body, increasing the levels of L-arginine, which can potentially treat the same conditions as L-arginine alone. Together, these amino acids can support:

  • Cardiovascular health
  • Boost nitric oxide production
  • Improve blood flow
  • Support healthy blood pressure
  • Bolster the immune system
  • Detoxify the liver
  • Enhance workout recovery
  • Improve sexual stamina

What's more, the two supplements appear to work synergistically to promote better health and performance. Not only do citrulline supplements absorb more efficiently than arginine supplements, but they also increase nitric oxide more when taken together. Taking L-arginine and L-citrulline together supplies the body with both immediate L-arginine and its L-citrulline precursor for sustained benefits. So, if you're looking to optimize your health, give L-arginine and L-citrulline supplements a try!

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How to Take L-arginine and L-citrulline Together?

Here are some tips on how to take them together:

  • Determine the appropriate dosage: The recommended dosage for L-arginine is 2 to 3 grams per day, while the recommended dosage for L-citrulline is 1 to 1.5 grams per day. It's important to follow these guidelines when taking these supplements to avoid any potential side effects.
  • Take L-citrulline first: L-citrulline is a precursor to L-arginine, so it's recommended to take it first. This allows the body to convert L-citrulline to L-arginine, which can then be used to produce nitric oxide.
  • Take L-arginine next: Once L-citrulline has been converted to L-arginine, it's important to take L-arginine to ensure that there's enough available to produce nitric oxide. This can help improve blood flow and support cardiovascular health.
  • Consider timing: It's best to take L-arginine and L-citrulline on an empty stomach to improve absorption. Some people also find it helpful to take them 30 minutes before exercise to enhance performance.
  • Stay hydrated: It's important to drink plenty of water when taking L-arginine and L-citrulline to prevent dehydration and support overall health.

Remember to speak to your healthcare provider before taking any new supplements to ensure that they are safe and appropriate for you.

People Also Ask For

  1. Why take L-citrulline and L-arginine together?

Taking L-citrulline and L-arginine together can be a good idea as they work synergistically in the body to maximize nitric oxide production. While L-arginine boosts nitric oxide production for cardiovascular, immune, and sexual health benefits, the body absorbs L-citrulline better than supplemental L-arginine, making it a better choice for supplementation. L-citrulline is also a good precursor to raise blood arginine levels for nitric oxide production as it is not easily broken down.

  1. What time of day should I take L-arginine and L-citrulline?

L-citrulline and L-arginine should be taken together to increase nitric oxide production. Citrulline can be taken one to three times a day on an empty stomach, 30-45 mins before exercise or bed, while L-arginine can be taken with food. Taking the two together can increase cardiovascular, immune, and sexual health benefits.

  1. Is L-arginine and L-citrulline good for erectile dysfunction?

Yes, L-arginine and L-citrulline can both be beneficial for treating erectile dysfunction. L-citrulline has been shown to be more effective than L-arginine supplements for increasing arginine levels in the body. A combination supplement of L-citrulline and L-arginine, or L-citrulline alone, can help with erectile dysfunction by improving blood flow and cardiovascular health, and boosting nitric oxide production. However, short-term use of L-citrulline may lower blood pressure, though results are mixed.

  1. Does L-arginine and L-citrulline increase testosterone?

While L-citrulline and L-arginine do not directly increase testosterone, L-citrulline has been shown to improve blood flow, increase nitric oxide levels, and ultimately support cardiovascular health. When L-citrulline and L-arginine are taken together, they can support cardiovascular health, boost nitric oxide production, help blood flow more easily, and detoxify the liver.

L-citrulline is also more effective than L-arginine supplements at increasing the levels of arginine in your blood, and can lead to lower blood pressure by causing blood vessels to dilate. Therefore, while these supplements may not increase testosterone levels, they can still offer potential health benefits.

Let’s Sum Up

L-Arginine and L-Citrulline are two amino acids that are essential for nitric oxide production in the body. The combination of both supplements can work wonders in increasing blood flow, reducing muscle soreness, and improving sexual health. Low levels of nitric oxide can lead to a host of health issues, from poor circulation and workout recovery time to lowered immunity and decreased sexual performance.

To take full advantage of these benefits, it's essential to take L-arginine and L-citrulline in the right doses at the right time. Consult with a healthcare expert to know more about how much and how to take L-arginine and L-citrulline together safely.


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