Super Pumped!! Citrulline and Glutathione Increases Blood Flow
L-citrulline supplementation has been shown to exhibit several beneficial effects on the cardiovascular system. Citrulline works in conjunction with L-arginine to enhance muscle blood flow. In a recent clinical study, l-citrulline supplementation dose-dependently increased plasma l-arginine levels in healthy human volunteers more effectively than equivalent doses of l-arginine itself. Furthermore, other researchers have demonstrated in clinical trials that l-citrulline supplementation functionally improves arterial stiffness, meaning it improved blood vessel dilation. So both work synergistically together but what according to research, combining the two work better than each one separately. In seems that a combining the amino acid L-citrulline and glutathione may boost nitrite and NO levels more than L-citrulline by itself.
Glutathione is an important antioxidant and plays a major role in the detoxification of endogenous metabolic products. Glutathione acts as a powerful antioxidant to preserve and protect the brain and other body tissues by protecting them from the damage of free radicals. It has been shown is some mammalian cell types, that glutathione and nitric oxide activity are linked. This suggests that glutathione may play an important role in protection against oxidative reaction of nitric oxide, thus contributing to the sustained release of nitric oxide. Therefore, combining L-citrulline with glutathione may augment the production of NO.